Research Use

  • MedFrontier FGF23 Intact
  • LeukoCompleteTM products

MedFrontier FGF23 Intact

MedFrontier FGF23 Intact assay is a microtiter plate format by the CLEIA technology to detect "Intact Fibroblast Growth Factor 23" specifically.

What is FGF23?

Intact Fibroblast Growth Factor 23 is the bioactive protein encoded by the FGF23 gene responsible for phosphate and Vitamin D metabolism.

Areas of FGF23 Research*

  • Rickets    X-linked hypophosphatemic rickets (XLH)
    Autosomal dominant hypophosphatemic rickets (ADHR)
  • Osteomalacia    Tumor-induced osteomalacia (TIO)
  • Kidney Disease    Chronic kidney diseas (CKD)
    Acute kidney injury (AKI)
  • Vitamin D Metabolism    Control of 1,25(OH)2 vitamin D homeostasis
  • Mineral Bone Disease    Hyperphosphatemia
    Iron deficiency
  • Cardiocvascular Disease    Left ventricular hypertrophy (LVH)

* Reference: Myles Wolf et. al. Curr Opin Nephrol Hypertens. 2014 Jul; 23(4): 411-419

Outlines

MedFrontier FGF23 Intact is a reliable, reproducible, and accurate serum blood test delivering optimum results quickly.

  • Measures intact FGF23, the full-length bioactive form of FGF23
  • Superior dynamic range of 10-3000 pg/mL
  • Excellent reproducibility
  • Microtiter plate assay
  • CLEIA technology
  • Only 20 μL serum

* MedFrontier FGF23 Intact is for Research Use Only. Not for use in diagnostics procedures.

* Only US and Canadian market available.

Please contact our US-based distributor, Eagle Biosciences at https://eaglebio.com/.

LeukoCompleteTM products

A series of LeukoCompleteTM products are specifically designed to evaluate cell mediated immune response by quantifying mRNA.

What is LeukoCompleteTM?

This kit is designed to detect genes derived from immune cells.
It allows for the simple extraction and purification of mRNA from leukocyte in the sample, as well as the synthesis of cDNA through reverse transcription of the purified mRNA. The synthesized cDNA can be used to evaluate relative changes in gene expression through quantitative PCR (qPCR)or similar methods.

Protocol

Described below is a workflow with LeukoCompleteTM products comprising 2 parts cDNA preparation with LeukoCompleteTM Plate and RT Kit (Part A) and RT qPCR with LeukoCompleteTM Gene Detection Kit (Part B).

Outlines

  • An all-in-one kit optimized for the quantitative assessment of cellular immunity using gene expression as an indicator.
  • Whole blood samples can be used without pretreatment.
  • Antigen stimulation takes only 4 hours.
  • Whole blood samples can be stored frozen after stimulation.
  • No need for a dedicated analyzer (in-house qPCR compatible)
  • Requires only 100µL of whole blood per well.
  • Customizable in terms of sample types and target genes, highlighting its potential use in various applications.

* LeukoCompleteTM is for Research Use Only. Not for use in diagnostics procedures.